A few studies provided evidence that EDA can be used to differentiate acutely suicidal subjects from depressed patients who are not severely suicidal. There is also preliminary evidence that monitoring EDA may help to differentiate the phases of mood disorders. The studies were fairly consistent in maintaining that hypoactive electrodermal response is an established feature of patients affected by depression. Resultsġ287 articles were screened and 77 relevant studies were identified and included in the systematic review. A preliminary synthesis of findings was developed using tables, thematic analysis and quality ratings. The initial screening of articles was based on titles and abstracts then the full text was reviewed. We searched MEDLINE, Scopus, Cochrane Library, and Web of Science databases, following PRISMA guidelines. We aimed to review EDA research systematically, focusing on EDA’s usefulness as a biomarker for depression and suicidal behaviour. Electrodermal activity (EDA) and other peripheral autonomic electrical parameters have been used as indicators of emotional states, including depressive states and suicidal state.
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